Cullin_2 domain-containing protein
WebMar 21, 2024 · DCUN1D4 (Defective In Cullin Neddylation 1 Domain Containing 4) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Class I MHC mediated antigen processing and presentation . An important paralog of this gene is DCUN1D5. UniProtKB/Swiss-Prot Summary for DCUN1D4 Gene WebNov 10, 2000 · F-box proteins contain a wide range of secondary motifs including zinc fingers, cyclin domains, leucine zippers, ring fingers, tetratricopeptide (TPR) repeats, and proline-rich regions. The diversity of …
Cullin_2 domain-containing protein
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WebMar 21, 2024 · DCUN1D1 (Defective In Cullin Neddylation 1 Domain Containing 1) is a Protein Coding gene. Diseases associated with DCUN1D1 include Squamous Cell Carcinoma and Scrotum Squamous Cell Carcinoma . Among its related pathways are Metabolism of proteins and protein neddylation . An important paralog of this gene is … WebApr 16, 2024 · The BTB domain, also known as POZ (poxvirus and zinc finger) domain, is a protein-protein interaction motif in eukaryotes [ 12]. All eukaryotes have a large variety of proteins that contain a BTB/POZ domain.
WebHere we identify Skp2 as a component of an Skp1-cullin-F-box complex that is based on a Cul1-Ro52 RING finger B-box coiled-coil motif family protein catalytic core. Ro52-containing complexes display E3 ligase activity and promote the ubiquitination of Thr187-phosphorylated p27 in a RING-dependent manner in vitro. WebUbiquitin-conjugating Enzyme E2M (UBE2M), also known as Ubiquitin-conjugating Enzyme 12 (Ubc12), is a ubiquitously expressed protein with a predicted molecular weight of 20 kDa. UBE2M/Ubc12 is highly conserved, and the human ortholog shares 100% amino acid identity with mouse and rat UBE2M. UBE2M/Ubc12 mediates conjugation of the …
WebProtein target information for CULLIN_2 domain-containing protein (zebra finch). Find diseases associated with this biological target and compounds tested against it in … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules)
WebBy examining genes arising from intra- and interchromosomal duplications involving the ancestral chromosome 2 fusion site, followed by PCR of a fetal brain cDNA library, Fan …
WebCul2 and Cul5 are the most structurally related among the cullins and use elongins B and C as adaptors to engage a variable substrate recruitment protein. Among the most well-studied substrate recruitment proteins are … round bale nets for horsesWebNext-day shipping cDNA ORF clones derived from AURDEDRAFT_77860 Cullin-domain-containing protein available at GenScript, starting from $99.00. ... TurboCHO™ High Throughput Services as fast as 2 weeks; TurboCHO™ Protein Expression ... sgRNA Services; Gene Synthesis; mRNA Synthesis New! Gene to Lentivirus One Stop Package … round bale netting for horses canadaWebOct 2, 2024 · To date, at least 70 F-box protein receptors have been identified for CRL1, a handful of VHL domain-containing proteins for CRL2: approximately 180 BTB proteins … round baler belt trackingWebCullin-RING ligases (CRLs) recognize and interact with substrates for ubiquitination and degradation, and can be targeted for disease treatment when the abnormal expression of … round baler belting and accessoriesWebNov 5, 2013 · Abstract The tumor suppressor VHL (von Hippel-Lindau) protein is a substrate receptor for Ubiquitin Cullin Ring Ligase complexes (CRLs), containing a BC-box domain that associates to the adaptor Elongin B/C. VHL targets hypoxia-inducible factor 1α to proteasome-dependent degradation. round balerWebCRLs are multisubunit complexes containing a cullin (CUL1-7) as scaffold protein, a RING domain protein Rbx1 or Rbx2, an adaptor protein, and a substrate recognition subunit … strategic planning process for nonprofitsWebApr 28, 2011 · Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins involving ubiquitin. The mammalian cullin … round baler for sale in ni